CFDE Partnerships

The CFDE has funded collaborative DCC partnership projects that will develop approaches and tools to harmonize data and workflows from multiple Common Fund programs enabling cross-dataset analysis. These partnerships are meant to enhance DCC-DCC interactions. In addition, these partnerships aim to demonstrate the utility of their data integration tools and approaches for CF datasets to the broader scientific community.

Active CFDE Partnerships

P

Playbook Workflow Builder

active

This project develops an interactive workflow engine that draws knowledge from across CF DCCs using their APIs.

Participating DCCs:

D

Data Distillery Knowledge Graph

active

This partnership assembles a knowledge graph database by integrating assertions from across the CFDE DCCs to enable cross-DCC knowledge discovery.

Participating DCCs:

B

Biomarker

active

The Biomarker Working Group (BWG) will produce a common, harmonized, integrated, biomarker definition and data model framework (all participating DCCs).

Participating DCCs:

S

Standard RNA-Seq Pipeline

active

This project produces a standarized RNA-seq alignment pipeline for the CFDE to increase the FAIRness and interoperability of RNA datasets across the CFDE.

Participating DCCs:

C

Cloud Workspace Pilot

active

The goal of the Kids First CFDE “Cloud Workspace Partnership Pilot” is to understand valuable data, tool and research use cases of other CFDE DCCs and collaboratively pilot integration of data and tool usage in the CAVATICA cloud workspace.

Participating DCCs:

C

COMPA

active

The Communication and Outreach to Maximize Product Adoption (COMPA) aims to maximize CFDE product adoption by carrying out market research, dissemination, and user recruitment for CFDE products.

Participating DCCs:

Past CFDE Partnerships

G

Gene Centric Prototype Dashboard

completed

This project developed methods to harmonize gene, protein, and variant identifiers across the CF DCCs by integrating DCC APIs and gene landing pages.

Participating DCCs:

R

Reproductive Toxicology Screening Pipeline

completed

This project developed a knowledge graph that connects genes, birth defects, and drugs to discover reproductive toxicity potential for preclinical compounds.

Participating DCCs:

C

Clinical Observations and Vocabularies (CLOVoc I & II)

completed

The goal of the CLOVoc project was to improve the querying clinical data across CF datasets enabling secondary analyses that drive insights about health and disease.

Participating DCCs:

M

Making Gene Regulatory Knowledge FAIR

completed

The project focuses on gene regulatory elements as the key “stepping stone” for connecting genes, pathways, and regulators in tissue-specific, developmental, and disease contexts.

Participating DCCs: