Discover, Analyze, and Integrate NIH Common Fund Data
The NIH Common Fund programs generate diverse datasets from a variety of projects ranging from genomics to phenotypes. The Common Fund Data Ecosystem (CFDE) aims to facilitate improved discovery, reuse, integration, and analyses of these datasets to form novel hypothesis for accelerating discoveries in biomedical research.
PRODUCTS, PARTNERSHIPS, & EVENTS
The Common Fund Data Ecosystem (CFDE) aims to enable broad use of data generated by Common Fund Programs to accelerate hypothesis generation and discovery.
TRAINING & OUTREACH
CFDE Webinar Series
The CFDE Webinar Series brings the varied programs of the CFDE to the broad biomedical research community. Join us on the last Friday of each month at 1-2 PM ET to learn the science behind the research programs that comprise CFDE, as well as about the CFDE as a whole and its coordination Centers.
Starts: May 31, 2024
Making data more FAIR
The Data Resource and Knowledge Centers are dedicated to enhancing the accessibility and utility of Common Fund-generated data and resources, striving to uphold the FAIR principles. This commitment serves as a catalyst for groundbreaking biomedical discoveries, fostering synergies across the diverse datasets within the Common Fund ecosystem, thereby unlocking novel avenues of research and innovation.
Findable
Accessible
Interoperable
Reusable
Social Media
Working to improve findability, accessibility, and interoperability of NIH Common Fund data sets and to encourage data reuse.
Check out this APS webinar on our YouTube channel. In this webinar, Maryann Martone, PhD, and Peter Hunter, PhD, explore the SCKAN knowledge base, SPARC Knowledge Graph and uses of the portal for a wider range of physiological processes. bit.ly/3TyOm1C @APSPhysiology
Tune in 5/20 at 2:30 PM ET! #Bridge2AI Investigator Dr. Lee (@aaronylee) will share insights from his work on creating an ethically-sourced #AI #dataset for #Type2Diabetes (#salutogenesis). Register today for this webinar hosted by @NatEyeInstitute: bit.ly/3K7Pxik
Unlock momentous insights with Dr. David Teachey, specializing in cancer and blood diseases, at the #KidsFirst Spring Webinar! He brings epic scientific work on Leukemia using Kids First data to the panel discussion. Register now: buff.ly/3JYlslA @NIH_CommonFund 
Unlocking the mysteries of childhood diseases by studying #ChildhoodCancer and #CongenitalDisorders together, #KidsFirstDRC and #KidsFirst researchers find common threads in the body's code. Together, we can fight for healthier futures. 
Project Pitch is now open for the 2024 SPARC FAIR Codeathon! Show off your coding skills in this 3-day virtual challenge! It's free to enter, and there's $50k up for grabs. Leverage SPARC tools and data in innovative ways. bit.ly/436EHlt #data #openscience #python #code 
New from #NIHHighRisk: scientists have found a new way to grow #kidney cells that can help learn more about important #genes and find new treatments for #KidneyDisease. Read more in the highlight: go.nih.gov/Ivt7Qfc 
Register today for a technical webinar on May 22nd at noon ET. We will be discussing the open Research Opportunity Announcement for integrating #ClinicalResearch into #PrimaryCare. Register now bit.ly/3Uw05gk 
Want to learn more about how to measure and monitor #representation in #biomedical #datasets? Then join #Bridge2AI project staff as we tune in on 5/21 at 3PM ET to learn about the @MIDRC_ #Diversity Calculator. Register: us06web.zoom.us/webinar/regist…
Did you miss the webinar on the implementation of the simplified review framework for RPGs? The resources are now available! ▶ nexus.od.nih.gov/all/2024/05/15… 
#KidsFirst virtual office hours are now held in collaboration with @velseraofficial and the #INCLUDEDCC. Tomorrow, get your technical questions answered by our experts and learn more about leveraging these great resources: buff.ly/3qxhLwy
@NIH_CommonFund 
Early bird registration for ISAN closes on Tuesday, May 27th. Don't miss out—register today! bit.ly/44IlHdP #NIH_SPARC #OpenData #ISAN2024 #OpenScience 
Join us for the #KidsFirstDRC Spring Webinar on May 29 @ 11 A.M. EDT and get an exclusive sneak peek at our new portal! Don't miss out - register now: buff.ly/3JYlslA
@NIH_CommonFund 
Join #KidsFirst and @kidsfirstDRC on May 29 from 11 AM-12PM ET for a transformative look into #pediatric research at the Spring Webinar, “Big Data Dialogue, The Next Catalyst for Cures.” Live demos & insightful discussions await. Register: nih.zoomgov.com/meeting/regist…
#TogetherWeRise 
Are you interested in #neurosurgery research? Check out this article by our #NIHHighRisk Research Program #NewInnovator awardee Shadi Dayeh and colleagues who developed a new tool to visualize brain activity. Learn more: pubmed.ncbi.nlm.nih.gov/38657026/ 
Don’t miss your chance to take a PUPPY (#PuppyCam) break for your #MentalHealth (@NIMHgov). Try it out in honor of #MentalHealthAwarenessMonth
This just in: #NIHCommonFund's Acute to Chronic Pain Signatures #A2CPS has published a paper on ways researchers can standardize and analyze #pain scores to make #ChronicPain research "clinically meaningful"!
The #NIHCommonFund is hosting a public half-day webinar on 6/7, starting at 10am ET to review results of #ListeningSessions to inform NIH’s vision for the future of #ClinicalResearch in #PrimaryCare. Want to hear what the participants said? Register today! bit.ly/3R8DIwD 
Did you miss today’s technical assistance webinar for integrating #ClinicalResearch into #PrimaryCare? It’s not too late to register to attend the Technical Assistance Webinar scheduled for May 22nd at 12pm ET. Register today! bit.ly/3Uw05gk 
Come join us for a webinar presented by Dr. Yan Li on Friday, May 17, 2024 to learn more about this useful resource "Beta Cell Hub"! bit.ly/3wwLBVr @dkNET_Info #NIH_SPARC #opendata 
This #BrainTumorAwarenessMonth, #KidsFirst is using the power of data. Our curated datasets include information on #Cancer predisposition, helping researchers identify genes linked to a higher risk of brain tumors. Earlier detection saves lives. #KidsFirstDRC #CuresStartHere 
#PrimaryCare is intended to be the setting for #prevention and everyday health care. Read about a new opportunity to explore the integration of #ClinicalResearch into everyday care: go.nih.gov/ExTIXPY 
Explore the innovative science proposed by the #ComplementARIE Challenge prize winners. Read the unconventional ideas from challenge solvers using #insilico #inchemico and #invitro approaches to #NewApproachMethodologies: go.nih.gov/Complement-ARI… 
It's been two weeks since the first ever IMPC Spring meeting that took place in South Africa. If you want to have more insight on the meeting, read our most recent news letter post!
mousephenotype.org/news/beyond-th…
#IMPC #BeyondtheGenome #IMPCConferences24
Join us on 5/21 at 3PM ET for the #Bridge2AI AI READI (#Salutogenesis) monthly webinar! Learn about the rapidly evolving legal and regulatory landscape of #AITechnology for #healthcare (#medicine). Join by Zoom: bit.ly/4arolWV. 
Exciting news! ARPA-H has unveiled 2 new funding opportunities: the LIGHT program and Mission Office-specific ISOs. Learn more on our Funding Announcements page. Apply today! bit.ly/SPARCfunding @ARPA_H #opendata #funding #NIH_SPARC #OpenScience
Exciting news! A2CPS has published online in @PAINthejournal with a statistical analysis of reports of acute and #chronicpain journals.lww.com/pain/abstract/…
It’s not too late to register for the first technical assistance webinar to discuss Integrating #Clinical Research into #PrimaryCare. Join us tomorrow! bit.ly/3UP0wUi 
Join us on Thursday, May 16 from 1-2 PM ET for a webinar on Sharing Data in HEAL-compliant Repositories. Featuring insight from Dr. Nora Volkow of NIDA, HEAL Steward Allie Gartland-Gray, and HEAL Platform's Dr. Brienna Larrick. Live Q&A included. bit.ly/4bvm5i9 #opendata 
Join us on May 29 @ 11 A.M. ET for a transformative look into pediatric research at the #KidsFirst Spring Webinar, “Big Data Dialogue, The Next Catalyst for Cures.” Live demos and insightful discussions await. Secure your spot now: buff.ly/3JYlslA
@NIH_CommonFund 
Don't forget to join @Bridge2aiVoice for this webinar on #Voice (#AI) #Biomarkers and #Validity on 5/14 at 3:30 PM ET. Log in to MS Teams: bit.ly/3WzI1Ep. ID: 21218237539. Passcode: JSTvnL. #Bridge2AI 
Only two days left to apply to the #NIHCommonFund’s SysBio Venture Initiative #ResearchOpportunity Announcement! Submit your applications now: commonfund.nih.gov/venture/sysbio 
Only two more weeks to apply to the #NIHCommonFund’s #Oculomics #ResearchOpportunity Announcement. Submit your applications today!: commonfund.nih.gov/venture/oculom… 
🔔 Have questions about PCORI’s new funding opp: Addressing Rare Diseases? Attend the Applicant Town Hall on May 14 & ask the experts. Register now: pcori.me/3OGOn02 
Did you miss the SPARC #Python Webinar? Stream it now on YouTube! Se the new SPARC Python Client and learn to navigate public datasets, download #data, and leverage the Open Simulation Platform for Advanced #Research (o²S²PARC) for data transformation. bit.ly/3UrXdRi
Register today to join the conversation May 29th, 11AM-12PM ET! We'll be diving into #research for kids at the #KidsFirst Spring Webinar, “Big Data Dialogue, The Next Catalyst for Cures,” Live demos and insightful discussions are ahead. Register today! nih.zoomgov.com/meeting/regist… 
Join @Bridge2aiVoice for this webinar on #Voice (#AI) #Biomarkers and #Validity on 5/14 at 3:30 PM ET. Log in to MS Teams: bit.ly/3WzI1Ep. ID: 21218237539. Passcode: JSTvnL. #Bridge2AI 
Don’t forget to join us for a technical assistance webinar on integrating #ClinicalResearch into #PrimaryCare settings. It’s happening on Tuesday, May 14, at noon ET. Register today bit.ly/3UP0wUi 
Do you want to communicate with your inner cellf, but can't find the way? Then check out the new maps published in @CellCellPress by @KaiTanLab1 @ChildrensPhila, showing where different cell types reside in bone marrow, digging deep ditches to find the niches! 
Bringing together childhood cancer and congenital disorder registries can save lives. Hear what AACR NIH booth presenter Dr. Adam Resnick said about how collaboration transforms diagnostics and treatment: buff.ly/3QzC2fi
#KidsFirstDRC
🔬 Congratulations to Dr. William Gahl and the entire UDP team for this feature in the Washingtonian magazine!
Access the article in Washingtonian's March 2024 Issue: Cool Jobs at bit.ly/3wufQME
#UDN #UDP #Genetics #RareDiseases #NIH #MedicalMysteries 
Announcing the #ComplementARIE Challenge Prize winners! Read about these out-of-the box ideas that could advance the field of #NewApproachMethodologies and how they will help inform the Complement-ARIE program: go.nih.gov/Complement-ARI… 
🚀 Funding Opportunity Alert! @NIH_CommonFund seeks applications (RFA-RM-24-006) for Pilot Projects enhancing utility & usage of Common Fund data sets. Early Stage Investigators encouraged! #ResearchFunding #NIH
Deadline: June 27, 2024
Details: bit.ly/3JflHbj 
A new #FundingAnnouncement looks to increase access to #ClinicalResearch by bringing it to #PrimaryCare settings. Learn more about the new opportunity: go.nih.gov/xS0qccThttps:/… 
Register for a Technical assistance webinar on 5/14/24 at 12PM ET to learn more about an NIH #FundingOpportunity to enable access to #ClinicalResearch: bit.ly/3UP0wUi 
#ICYMI Register by tomorrow, May 10th for the #Transformative Research to Address #HealthDisparities and Advance #HealthEquity (THD) Program's webinar highlighting three of their research projects!
Why do phosphate-containing medications cause itch? MRGPRX4!
Latest @RothLabUNC @Cannabatopia and Dong Lab (HHMI/Hopkins) collaboration:
doi.org/10.1126/scitra…
Rare GPR37L1 Variants Reveal Potential Association between GPR37L1 and Disorders of Anxiety and Migraine jneurosci.org/content/44/19/…
Learn more about last week's 2024 @Bridge2aiVoice Symposium and the impact of #AI (#ML) in voice #biomarker research. #Bridge2AI
Come join us for a webinar presented by Dr. Andrew Schroeder on Friday, May 10, 2024 to learn more about this useful resource "4DN Data Portal"! bit.ly/3UoNsTW @dkNET_Info #NIH_SPARC #opendata 
Looking for ways to learn more about biomedical data? Well how about signing up for an online course offered by CFDE with IDG scientific use cases. Starts June 3rd!
Learn more at: datascience.unm.edu/isbdscourse_cf… 
🚨Data release alert!
Data release 21 is live on the IMPC web portal. Phenotyping data is available for 8,707 genes with around 2.4 million new data points!
For more: mousephenotype.org/news/data-rele…
#mousegenetics #data #IMPC #genetics
The UDN is hosting a virtual educational course titled “Evaluation of Undiagnosed and Rare Conditions”.
This training program aims to teach methods of undiagnosed patient evaluation to students, clinicians, and researchers.
Register for the course here: tinyurl.com/yckeupmh 
Interested in #ClinicalResearch and #PrimaryCare? The Common Fund has announced a new #ResearchOpportunity that hopes to integrate #research into primary health care settings. Read more about the pilot program and Research Opportunity Announcement. go.nih.gov/xS0qccT 
Get set for the 2024 SPARC FAIR Codeathon! Demonstrate your coding prowess in this three-day virtual competition! Registration is free, and there's a chance to win $50k. Utilize SPARC tools and data creatively. Register to learn more: bit.ly/436EHlt #data #openscience 
New from the #4DNucleome program: immune cells like #neutrophils depend on large loops in their #DNA to activate genetic pathways that determine their identity. Read more: go.nih.gov/tW4KPJu https://t.co/1TbhSfs4a4
The #ComplementARIE Challenge prize winners have been announced! Learn about the winning solutions that could revolutionize the field of #NewApproachMethodologies: go.nih.gov/Complement-ARI… 
Do you like to use #biomedical #data in your #research? The #NIH_CFDE is accepting #pilotproject #research proposals using #NIH_CommonFund #data. Deadline approaching 6/27. go.nih.gov/e2d3YMc 
Please join us this Thursday (05/9/24) at 1 p.m. ET for UDN Grand Rounds hosted by the University of Utah clinical site. View the full schedule and register undiagnosed.hms.harvard.edu/events/………… #FreeCME #GrandRounds
Our May issue is live! Read about RNA-editing drugs, therapeutics for tuberculosis, small-molecule prodrugs, RNAi-based drug design and more here bit.ly/3wtet0H 
đź”” It starts TODAYđź””
New Research Funding Announcement 📷 Interested in proposing a patient-centered CER project on rare diseases? Check out @PCORI’s new Addressing Rare Diseases PFA! Up to $100M in available funding: pcori.me/3SFCmJl 
New study highlights bone marrow atlas from @CHOP_Research & @PennMedicine offers unprecedented window into blood production. This could lead to major advances in treating bone marrow disorders:
ms.spr.ly/6016YpTRM. 
Thank you to everyone who joined us in Bethesda, MD for the #SenNet Consortium Spring Meeting! Two great days of discussions, strategy, and updates centered on #senescence research.
See you in California this September for the fall conference! 
Submit your research for #SfN24 before abstracts close tomorrow! Don't miss this chance to share and collaborate with experts worldwide in researching the body and brain. Join SPARC at SfN 2024 and pay us a visit at booth #1764! bit.ly/49JeCup @SfNtweets #opendata 
Only one week left to submit your applications to the #NIHCommonFund’s #SysBio #ResearchOpportunity Announcement! Contribute to this exciting initiative by submitting your plans for #dataset integration today: commonfund.nih.gov/venture/sysbio 
🔔 Interested in submitting an LOI for @PCORI’s upcoming funding opp., Addressing Rare Diseases? Attend the Rare Diseases PFA Applicant Town Hall on May 14 to learn everything you need to submit a responsive LOI: pcori.me/3OGOn02 
The new updates to the SPARC Portal highlight the introduction of the "SPARC App" category in the portal header, serving as the centralized location for all applications developed by SPARC, including Maps, along with various other improvements. bit.ly/3tNVXi7 #opendata 
The #NutritionforPrecisionHealth study, powered by @Allofus was featured today on Good Morning America (@GMA)! Watch as reporter Becky Worley takes part in this effort to advance precision #nutrition. Enrollment is open! goodmorningamerica.com/wellness/video…
📢 New Research Funding Announcement 📷 Interested in proposing a patient-centered CER project on rare diseases? Check out @PCORI’s new Addressing Rare Diseases PFA! Up to $100M in available funding: pcori.me/3SFCmJl 
Interested in reading more of the findings highlighted in the #MoTrPAC paper package released this week? Check out this study on mitochondrial responses to #exercise across the body's tissues! Read more: sciencedirect.com/science/articl…
#MoTrPAC has some interesting findings on how #exercise impacts #genetics. Dig into the article published this week: pubmed.ncbi.nlm.nih.gov/38693125/
How do molecules of specific parts of the body change in response to #exercise training? #MoTrPAC has some early findings. Learn more: pubmed.ncbi.nlm.nih.gov/38697122/
How does the body change in response to endurance exercise? Check out the early findings from the #MoTrPAC In Press article: doi.org/10.1093/functi…
Curious how sex difference can affect how #exercise impacts the body? #MoTrPAC has some early results you might find interesting. Read more from the paper package published this week! pubmed.ncbi.nlm.nih.gov/36778330/
Due to high demand the registration for the Data API workshop has been closed. But if you're interested, don't worry! You can register interest to be on the waiting list and to scope for interest for another session.
For more: mousephenotype.org/blog/2024/04/1…
#IMPCWorkshops24 #API #SOLR
Webinar May 7. This virtual series will review updates in the OpenNerve Platform, an open-source implantable device that stimulates & records the peripheral nervous system, focusing on the vagus and sacral nerves. Register now: bit.ly/3vOsVjH #opendata @USC 
We presented GlyGen and CFDE at the 2024 Georgia Glycoscience Symposium at the Complex Carbohydrate Research Center.
ccrcweb.wixsite.com/ggs2024
@CfdeNih 
Exercise may be the single most potent medical intervention ever known. Its benefits in prevention outstrip any known drugs: 50% reduction in the risk of cardiovascular disease, 50% reduction in the risk of many cancers, positive effects on mental health, pulmonary health, GI 
#MoTrPAC researchers have been featured again in a publication highlighting the key factors that impact the body's response to #exercise. Read their findings pubmed.ncbi.nlm.nih.gov/38262420/
The three-dimensional shape of our #DNA controls how cells operate, but how does that work in cells that dramatically change their shape like #neutrophils? #4DNucleome researchers have found new insights the DNA of these cells. Read more: go.nih.gov/tW4KPJu 
The UDN is hosting a virtual educational course titled “Evaluation of Undiagnosed and Rare Conditions”.
This training program aims to teach methods of undiagnosed patient evaluation to students, clinicians, and researchers.
Register for the course here: tinyurl.com/yckeupmh 
‼ Join Dr. Nora Volkow from @NIDAnews at the Fresh FAIR webinar on May 16, 1:00 PM. Learn about depositing data into HEAL repositories, gaining insights and resources for investigators. Don't miss out on this crucial call-to-action for the HEAL community!
bit.ly/4bbpuCG 
Excited to see the first 5 papers published from our MoTrPAC Study Group. Paper #1 in Nature: nature.com/articles/s4158…
Editorial: nature.com/articles/d4158… 
A new study by the Molecular Transducers of Physical Activity Consortium (MoTrPAC) identifies thousands of molecular changes that collectively offer insight into the benefits to immune, metabolic and stress-response pathways as the body adapts to exercise nature.com/articles/s4158…
Our latest paper, "Temporal Dynamics of the Multi-omic Response to Endurance Exercise Training", is now published in @Nature.
Dive into our comprehensive study mapping the molecular cross-tissue responses to exercise: nature.com/articles/s4158…
Congrats to the MoTrPAC team!
Check out the new #Bridge2AI theme #song composed by Dr. Chen with the use of #AITechnology! This song celebrates #AI (#ML) in #biomedicine and won 1st place at the Washington, D.C. conference. bridge2ai.org #aimusic 
While #MoTrPAC’s most recent study results are from animal models, researchers are currently conducting an #ExerciseStudy in people of different ages, sexes, body compositions, and fitness levels. Interested? Read more: motrpac.org/join/informati… 
The Common Fund’s programs drive #openscience through developing open access datasets. #MoTrPAC’s research in #ExerciseScience has not only resulted in amazing findings, but a large dataset of molecular changes found after exercise. Explore the data here! 
“This is an unprecedented large-scale effort to begin to explore—in extreme detail—the biochemical, physiological and clinical impact of exercise,” -Dr. Tracy of @uvmvermont, #MoTrPAC's biorepository. Explore UVM's contributions: eurekalert.org/news-releases/…
Rummagene is a search engine for gene sets, created by extracting human and mouse gene sets from supporting materials of >120,000 biomedical research publications: nature.com/articles/s4200… @AviMaayan @MaayanLab 
Save the date: 📅 May 8, 2024 🕒 3–4 pm CEST
Online #BeilsteinTalk "Chemical precision tools to dissect protein #glycosylation" with @DrGlycoBen @TheCrick @impchemistry.
Participation is FREE! Just register: 🔗beilstein-institut.de/en/talks/bioch…
#glycotime #chembio #BeilsteinTalks 
Always love to see new things from @AviMaayan et al. Rummaging through online papers in order to scrape the as of yet inaccessible supp tables is super smart. And such a good name (obviously).
nature.com/articles/s4200…
Want to see how spatial profiling techniques have given biologists, including @_hubmap’s own Dr. Andrea Radtke from the #GermainLab and @NIAIDNews, never before seen views of cells and tissues? Then set your sights here: optica-opn.org/home/articles/…
Planning for #USASP2024? Be sure to catch #A2CPS investigator @torwager at a symposium, "Unlocking the Social Neuroscience of Pain: Trust, Learning, and Support" with Luana Colloca and Przemysław Bąbel on Mon at 3:30 - see you there!
📢 dkNET #Webinar Slides Now Available!
#dkNET has slides available from the webinar on March 22, 2024 "Tabula Sapiens" presented by Dr. Angela Oliveira Pisco.
#cellulardiversity #genome #humanatlas #transcriptome #geneexpression
Slide link: slideshare.net/slideshow/dkne…
Thank you, @AACR, for another terrific annual meeting. We enjoyed sharing our research, learning from others, and connecting with the community of people working to advance #CancerResearch. We look forward to seeing you again next year! #AACR24 #NCIFuture 
The NIH Common Fund is requesting research applications encouraging the use of Common Fund data. To be eligible, the proposed research must substantially leverage data from at least two Common Fund programs.
grants.nih.gov/grants/guide/r…
Don't miss out on the #NIHHighRisk Research Program #FundingOpportunity webinars! If you are an #innovative researcher at any career stage, register today to learn more about applying for these opportunities. See more: commonfund.nih.gov/highrisk 
Did you miss the #KidsFirst Pediatric Data Hour at #AARC24? It’s not too late to visit booth #3759 for a demo of the #Data Portal with the @kidsfirstDRC. 
Have you registered for our #webinar on “Unlocking the Power of FAIR Data Sharing With ImmPort”?
Check out the #dkNET blog below for info: dknet.org/about/blog/2729
#datasharing #FAIRdata #immunology #datamanagement 
CBTN posters represented at #AACR2024 in San Diego! Dr. Ali Nabavizadeh of @ChildrensPhila, along with the translational imaging research team, utilize imaging and advanced bioinformatics methods to gain insights about pediatric #LGG biology to improve outcomes. #wearecbtn 
Have you registered for next week's webinar on how the new simplified review framework will impact funding opportunities? đź’ Join NIH experts for live Q&A: go.nih.gov/S4hfVUq #NIHgrantsevents 