Library of Integrated Network-based Cellular Signatures (LINCS)
The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program developed a library that catalogs changes that occur when different types of cells are exposed to a variety of agents that disrupt normal cellular functions, called “perturbagens.” This library integrated data across cell types, perturbagens, and measurements of cellular responses for use by scientists to design and conduct experiments that can help us better understand normal and diseased cellular states and how to alter them. (Retrieved from the NIH Common Fund site)
TRAINING & OUTREACH
Summer Research Program in Biomedical Big Data Science
The LINCS DCC Summer Research Training Program in Biomedical Big Data Science is a research intensive ten-week training program for undergraduates interested in bioinformatics. Summer fellows training in the Ma’ayan Lab at the Icahn School of Medicine at Mount Sinai conduct faculty-mentored research in the areas: data harmonization, machine learning, cloud computing, and dynamic data visualization.
Application deadline: February 1, 2025
LINCS Summer Trainees Virtual Symposium 2024
This virtual symposium hosted by the Ma’ayan Lab and the Mount Sinai Center for Bioinformatics featured the accomplishments of 10 summer trainees during a 10-week research-intensive full-time training program. The projects covered topics such as data integration, data visualization, LLM integration, and knowledge graphs in the field of biomedical data science and bioinformatics, leveraging the power of AI and other computational tools and methods.
Starts: August 8, 2024
Metadata and Processed Data Files
C2M2
1 Current File(s) | 10 Archived File(s)
1 Current File(s)
10 Archived File(s)
Modified 9/18/2023
Current
Filename:
datapackage.zipCreator: LINCS
Filesize: 169.2 Mb
Date Modified: 9/18/2023
DCC Approved:
DRC Approved:
Archived
Filename:
datapackage.zipCreator: LINCS
Filesize: 166.0 Mb
Date Modified: 6/15/2023
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 166.7 Mb
Date Modified: 3/21/2023
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 166.2 Mb
Date Modified: 12/2/2022
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 165.5 Mb
Date Modified: 9/14/2022
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 164.2 Mb
Date Modified: 6/20/2022
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 171.1 Mb
Date Modified: 4/14/2022
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 171.1 Mb
Date Modified: 1/11/2022
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 131.1 Mb
Date Modified: 9/29/2021
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 141.3 Mb
Date Modified: 6/2/2021
DCC Approved:
DRC Approved:
Filename:
datapackage.zipCreator: LINCS
Filesize: 28.1 Mb
Date Modified: 3/24/2021
DCC Approved:
DRC Approved:
XMT
3 Current File(s) | 4 Archived File(s)
3 Current File(s)
4 Archived File(s)
Modified 9/14/2024
Current
Creator: LINCS
Filesize: 19.9 Mb
Date Modified: 9/14/2024
DCC Approved:
DRC Approved:
Creator: LINCS
Filesize: 14.9 Mb
Date Modified: 12/13/2022
DCC Approved:
DRC Approved:
Creator: LINCS
Filesize: 15.6 Mb
Date Modified: 12/13/2022
DCC Approved:
DRC Approved:
Archived
Creator: LINCS
Filesize: 87.4 Kb
Date Modified: 6/6/2022
DCC Approved:
DRC Approved:
Filename:
LINCS_L1000_Chem_Pert_up.gmtCreator: LINCS
Filesize: 15.5 Mb
Date Modified: 6/6/2022
DCC Approved:
DRC Approved:
Creator: LINCS
Filesize: 93.0 Kb
Date Modified: 6/6/2022
DCC Approved:
DRC Approved:
Filename:
LINCS_L1000_Chem_Pert_down.gmtCreator: LINCS
Filesize: 13.4 Mb
Date Modified: 6/6/2022
DCC Approved:
DRC Approved:
Attribute Tables
4 Current File(s) | 0 Archived File(s)
4 Current File(s)
0 Archived File(s)
Modified 3/29/2024
Current
Creator: LINCS
Filesize: 317.5 Mb
Date Modified: 3/29/2024
DCC Approved:
DRC Approved:
Creator: LINCS
Filesize: 1.4 Gb
Date Modified: 3/28/2024
DCC Approved:
DRC Approved:
Filename:
LINCS L1000 Chemical PerturbationsCreator: LINCS
Filesize: 33.6 Gb
Date Modified: 6/23/2021
DCC Approved:
DRC Approved:
Filename:
LINCS L1000 CRISPR PerturbationsCreator: LINCS
Filesize: 6.5 Gb
Date Modified: 6/23/2021
DCC Approved:
DRC Approved:
Archived
None Available
Knowledge Graph Assertions
1 Current File(s) | 1 Archived File(s)
1 Current File(s)
1 Archived File(s)
Modified 5/8/2024
Current
Archived
Filename:
LINCS.edges.csvCreator: LINCS
Filesize: 54.6 Mb
Date Modified: 10/26/2023
DCC Approved:
DRC Approved:
Interoperability Assets
ETL Scripts
2 Current File(s) | 0 Archived File(s)
2 Current File(s)
0 Archived File(s)
Modified 5/22/2022
Current
Archived
None Available
API Specifications
7 Current File(s) | 1 Archived File(s)
7 Current File(s)
1 Archived File(s)
Modified 1/31/2023
Current
Name:
SigCom LINCS Metadata (SmartAPI)
Creator: LINCS
Date Modified: 5/22/2022
DCC Approved:
DRC Approved:
Archived
Entity Pages
4 Current File(s) | 0 Archived File(s)
4 Current File(s)
0 Archived File(s)
Modified 3/8/2024
Current
Archived
None Available
PWB Metanodes
3 Current File(s) | 1 Archived File(s)
3 Current File(s)
1 Archived File(s)
Modified 2/26/2024
Current
Creator: LINCS
Date Modified: 2/7/2024
DCC Approved:
DRC Approved:
Creator: LINCS
Date Modified: 2/7/2024
DCC Approved:
DRC Approved:
Archived
Chatbot Specifications
0 Available Files
Current
None Available
Archived
None Available
Apps URLs
1 Current File(s) | 0 Archived File(s)
1 Current File(s)
0 Archived File(s)
Modified 6/11/2024
Current
Archived
None Available