CFDE Webinar Series

Join us on the last Friday of each month from 1-2 PM Eastern Time to learn more about how the CFDE is harmonizing and discovering new knowledge by integrating datasets, tools and other resources from a collection of NIH Common Fund programs.

Upcoming Webinars

More details will be added soon

Past Webinars

Friday, Jul 26, 2024

  • A Tour of the Human Reference Atlas v2.1

    Katy Börner

    Center Director for the Cyberinfrastructure for Network Science Center (CNS)

    Bruce Herr

    Technical Director for CNS

Friday, Jun 28, 2024

  • Illuminating the Druggable Genome (IDG) History and Background

    Jeremy Yang, Ph.D

    Research Associate Professor, UNM SoM, DoIM, TI Division

    Jeremy Yang, PhD, provides a brief overview of the workshop and the history and background of the IDG DCC. He explains the network of institutions and collaborators involved and introduces the IDG portal and Pharos data portal. He then covers how they categorize targets into four target development levels (TDLs).

    Relevant resources that will be discussed:
    IDG portal: https://druggablegenome.net/
    Pharos: https://pharos.nih.gov/
  • Illuminating the Druggable Genome (IDG) Importance and Impact

    Anna Waller, Ph.D.

    Scientist & Project Manager, UNM SoM, Dept of Pathology

    Anna Waller, PhD introduced the importance and impact of the IDG program. She explains the collaborative efforts within the IDG consortium. She then covered the research output, global collaborations, and outreach initiatives that have advanced the understanding of understudied proteins and their potential for clinical therapeutics.

  • DrugCentral, Exemplar and Featured IDG Knowledge Base

    Jayme Holmes

    Sr Engineer & Lead Developer, UNM SoM, DoIM, TI Division

  • Pharos, the IDG Data Portal

    Timothy Sheils

    Sr Engineer & Project Manager, NIH NCATS

    Timothy Sheils, a senior engineer at NIH NCATS, introduced the Pharos resource, covering how Pharos aggregated 78 data resources, the Pharos user-interface, filters, and ways to download and interact with the data using APIs.

    Relevant resources that will be discussed:
    Pharos: https://pharos.nih.gov/

Friday, May 31, 2024

  • Improved Methods to Query the LINCS L1000 Data

    Avi Ma'ayan, PhD

    LINCS Data Coordination Center and the CFDE Data Resource Center

    The Library of Integrated Network-Based Cellular Signatures (LINCS) was an NIH Common Fund program that was established to catalog how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by LINCS include experimental and computational methods, visualization tools, molecular and imaging data, and gene expression signatures. The presentation will cover LINCS datasets, tools, and a newly developed method to query the LINCS L1000 data for better prioritization of drugs, small molecules and single gene perturbations.

    Relevant resources that will be discussed:
    Rummagene: https://rummagene.com/
    SigCom LINCS: https://maayanlab.cloud/sigcom-lincs/
    Playbook Workflow Builder: https://playbook-workflow-builder.cloud/
  • Automatic Mining of Human and Mouse Gene Sets from GEO

    Giacomo Marino

    LINCS Data Coordination Center and the CFDE Data Resource Center

    RummaGEO is a web server application that enables gene expression signature search against thousands of human and mouse RNA-seq studies deposited into GEO. To enable such a search engine, an offline automatic process was established to identify the experimental conditions from uniformly aligned GEO studies available from ARCHS4. Once conditions are identified, differential expression signatures are computed to extract gene sets from these signatures. In total, RummaGEO currently contains 135,264 human and 158,062 mouse gene sets from 23,395 GEO studies. Overall, RummaGEO provides an unprecedented resource for the biomedical research community enabling hypothesis generation for many future studies.

    Relevant resources that will be discussed:
    RummaGEO: https://rummageo.com/
    ARCHS4: https://maayanlab.cloud/archs4/

Friday, Apr 26, 2024

  • Overview of the Common Fund Data Ecosystem

    George Papanicolaou, PhD

    NIH, CFDE Program Leader

    Christy Kano, PhD

    NIH, CFDE Program Officer

  • Metabolomics Workbench/National Metabolomics Data Repository

    Shankar Subramaniam, PhD and Mano Maurya, PhD

    Metabolomics Workbench DCC and CFDE Data Resource Center

  • CFDE and the Biomedical Research Community

    Noël Burtt and Kyle Gaulton, PhD

    CFDE Knowledge Center