Library of Integrated Network-based Cellular Signatures (LINCS)
The Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program developed a library that catalogs changes that occur when different types of cells are exposed to a variety of agents that disrupt normal cellular functions, called “perturbagens.” This library integrated data across cell types, perturbagens, and measurements of cellular responses for use by scientists to design and conduct experiments that can help us better understand normal and diseased cellular states and how to alter them. (Retrieved from the NIH Common Fund site)
TRAINING & OUTREACH
Accepting Application for the 2025 Summer Research Training Program in Biomedical Big Data Science
Application Deadline: February 1, 2025
Program Dates: June 2, 2025 – August 8, 2025
Starts: October 1, 2024
Metadata and Processed Data Files
C2M2
1 Current File(s) | 10 Archived File(s)
1 Current File(s)
10 Archived File(s)
Modified 9/18/2023
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Filename:
datapackage.zipCreator: LINCS
Filesize: 169.2 Mb
Date Modified: 9/18/2023
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Filename:
datapackage.zipCreator: LINCS
Filesize: 166.0 Mb
Date Modified: 6/15/2023
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datapackage.zipCreator: LINCS
Filesize: 166.7 Mb
Date Modified: 3/21/2023
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datapackage.zipCreator: LINCS
Filesize: 166.2 Mb
Date Modified: 12/2/2022
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datapackage.zipCreator: LINCS
Filesize: 165.5 Mb
Date Modified: 9/14/2022
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datapackage.zipCreator: LINCS
Filesize: 164.2 Mb
Date Modified: 6/20/2022
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datapackage.zipCreator: LINCS
Filesize: 171.1 Mb
Date Modified: 4/14/2022
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datapackage.zipCreator: LINCS
Filesize: 171.1 Mb
Date Modified: 1/11/2022
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datapackage.zipCreator: LINCS
Filesize: 131.1 Mb
Date Modified: 9/29/2021
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datapackage.zipCreator: LINCS
Filesize: 141.3 Mb
Date Modified: 6/2/2021
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datapackage.zipCreator: LINCS
Filesize: 28.1 Mb
Date Modified: 3/24/2021
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XMT
6 Current File(s) | 4 Archived File(s)
6 Current File(s)
4 Archived File(s)
Modified 12/19/2024
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Filename:
rummageo_chemical_perturbations.gmtCreator: LINCS
Filesize: 31.0 Mb
Date Modified: 12/19/2024
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rummageo_gene_perturbations.gmtCreator: LINCS
Filesize: 25.6 Mb
Date Modified: 12/19/2024
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l1000_cp.gmtCreator: LINCS
Filesize: 2.1 Gb
Date Modified: 12/11/2024
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Creator: LINCS
Filesize: 19.9 Mb
Date Modified: 9/14/2024
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Creator: LINCS
Filesize: 14.9 Mb
Date Modified: 12/13/2022
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Creator: LINCS
Filesize: 15.6 Mb
Date Modified: 12/13/2022
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Creator: LINCS
Filesize: 87.4 Kb
Date Modified: 6/6/2022
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LINCS_L1000_Chem_Pert_up.gmtCreator: LINCS
Filesize: 15.5 Mb
Date Modified: 6/6/2022
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Creator: LINCS
Filesize: 93.0 Kb
Date Modified: 6/6/2022
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LINCS_L1000_Chem_Pert_down.gmtCreator: LINCS
Filesize: 13.4 Mb
Date Modified: 6/6/2022
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Attribute Tables
4 Current File(s) | 0 Archived File(s)
4 Current File(s)
0 Archived File(s)
Modified 3/29/2024
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Creator: LINCS
Filesize: 317.5 Mb
Date Modified: 3/29/2024
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Creator: LINCS
Filesize: 1.4 Gb
Date Modified: 3/28/2024
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LINCS L1000 Chemical PerturbationsCreator: LINCS
Filesize: 33.6 Gb
Date Modified: 6/23/2021
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LINCS L1000 CRISPR PerturbationsCreator: LINCS
Filesize: 6.5 Gb
Date Modified: 6/23/2021
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Archived
None Available
Knowledge Graph Assertions
1 Current File(s) | 1 Archived File(s)
1 Current File(s)
1 Archived File(s)
Modified 5/8/2024
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LINCS.edges.csvCreator: LINCS
Filesize: 54.6 Mb
Date Modified: 10/26/2023
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Interoperability Assets
ETL Scripts
1 Current File(s) | 2 Archived File(s)
1 Current File(s)
2 Archived File(s)
Modified 11/23/2024
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Creator: LINCS
Date Modified: 11/23/2024
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API Specifications
7 Current File(s) | 1 Archived File(s)
7 Current File(s)
1 Archived File(s)
Modified 1/31/2023
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Name:
SigCom LINCS Metadata (SmartAPI)
Creator: LINCS
Date Modified: 5/22/2022
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Entity Pages
4 Current File(s) | 0 Archived File(s)
4 Current File(s)
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Modified 3/8/2024
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PWB Metanodes
3 Current File(s) | 1 Archived File(s)
3 Current File(s)
1 Archived File(s)
Modified 2/26/2024
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Creator: LINCS
Date Modified: 2/7/2024
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Creator: LINCS
Date Modified: 2/7/2024
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Chatbot Specifications
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Apps URLs
1 Current File(s) | 0 Archived File(s)
1 Current File(s)
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Modified 6/11/2024
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None Available
@CFDE Workbench 2025
The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
@CFDE Workbench 2025