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Extracellular RNA Communication (ExRNA)

The Extracellular RNA Communication program is exploring the biology of extracellular RNA (exRNA). Once thought to exist only within cells, in a paradigm shift for science, RNA is now known to be exported from cells as “extracellular RNA” and to play a role in cell-to-cell communication. Since its founding, the program has established data standards, a data portal, and tools and reagents available to the scientific community. The program cataloged exRNA molecules found in human biofluids like plasma, saliva, and urine from over 2000 donors. It also identified potential exRNA biomarkers for nearly 30 diseases, including cardiovascular disease, pregnancy complications, glaucoma, diabetes, and multiple types of cancer. (Retrieved from the NIH Common Fund site)

TRAINING & OUTREACH

CFDE Webinar Series

The CFDE Webinar Series will feature the exRNA DCC. The seminar will be about ‘Tools and methods for discovering disease-causing gene regulatory variants from WGS data with application to Congenital Heart Disease’ presented by Keyang Yu, a Genboree Research Assistant.

Starts: September 27, 2024

Biomarker discovery from extracellular (cell-free) RNA-seq and tissue of origin from GTEx RNA-seq profiles

Join us for an engaging hands-on workshop where Meenu Srinivasan of the Louise Laurent Lab at the University of California-San Diego will demonstrate how to perform integrative data analysis utilizing data from two Common Fund Data Ecosystem (CFDE) Data Coordinating Center portals followed by an interactive Q&A session.

Starts: September 12, 2024

Metadata and Processed Data Files

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  • Creator: ExRNA

    Filesize: 11.1 Mb

    Date Modified: 8/17/2023

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    Filesize: 10.7 Mb

    Date Modified: 3/23/2023

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    Filesize: 53.3 Mb

    Date Modified: 4/16/2022

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    Filesize: 7.0 Mb

    Date Modified: 1/21/2022

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    Filesize: 5.6 Mb

    Date Modified: 8/19/2021

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    Filesize: 5.4 Mb

    Date Modified: 6/11/2021

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  • Creator: ExRNA

    Filesize: 5.4 Mb

    Date Modified: 3/18/2021

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    ERCC.zip

    Creator: ExRNA

    Filesize: 461.4 Mb

    Date Modified: 5/8/2024

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    Filesize: 4.6 Gb

    Date Modified: 10/26/2023

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Interoperability Assets

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  • Name:

    CFDE Gene Regulatory Elements
    Template | Example

    Creator: ExRNA

    Date Modified: 10/3/2024

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  • Creator: DRC

    Date Modified: 10/19/2023

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    Creator: DRC

    Date Modified: 10/19/2023

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    Date Modified: 10/19/2023

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    Date Modified: 10/19/2023

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    Date Modified: 10/19/2023

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